2005, NucleaRDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation I174A was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | I174A | |
| Domain: | LBD HELIX 3 | |
| General numbering (NucleaRDB): | 338 | |
| Protein: | NR1I3_MOUSE (Nr1i3,Ca) | Swiss-Prot Cross-reference table Family page |
| Protein isoforms | 2 | |
| Other point mutations / same protein / same position | Point mutations at position 174 in NR1I3_MOUSE | |
| Other point mutations / same protein | List of mutations in NR1I3_MOUSE | |
| Family alignments |
1I3 Constitutive Androstane alpha (CAR1) 1I Vitamin D3-like (VDR,PXR,CAR) 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR | |
| Other point mutations / same position |
Position 174 in 1I3 Constitutive Androstane alpha (CAR1) family Position 228 in 1I Vitamin D3-like (VDR,PXR,CAR) family Position 221 in 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR family | |
| Reference: | The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Tzameli I, Pissios P, Schuetz EG, Moore DD Mol Cell Biol 2000 May;20(9):2951-8. | Medline |
| Other point mutations / same article | List | |
| Text source | HTML and PDF full texts | |
| Validation status | True positive |
Relevant sentences:
I174A
cmbi.kun.nl), 21-Apr-2005