2005, NucleaRDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation E318A was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | E318A | |
| Cited point mutation: | Glu318Ala,Glu318 | |
| Domain: | LBD HELIX 10-11 | |
| General numbering (NucleaRDB): | 1045 | |
| Protein: | NR1I3_HUMAN (NR1I3,CA) | Swiss-Prot Cross-reference table Family page |
| Protein isoforms | 2 | |
| Other point mutations / same protein | List of mutations in NR1I3_HUMAN | |
| Family alignments |
1I3 Constitutive Androstane alpha (CAR1) 1I Vitamin D3-like (VDR,PXR,CAR) 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR | |
| Other point mutations / same position |
Position 380 in 1I Vitamin D3-like (VDR,PXR,CAR) family Position 369 in 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR family | |
| Reference: | The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver. Zelko I, Sueyoshi T, Kawamoto T, Moore R, Negishi M Mol Cell Biol 2001 Apr;21(8):2838-46. | Medline |
| Other point mutations / same article | List | |
| Text source | HTML full text | |
| Validation status | Not yet checked |
Relevant sentences:
Glu318
cmbi.kun.nl), 21-Apr-2005