NucleaRDB: Extraction of mutation data from the literature

2005, NucleaRDB.

This data was extracted from Medline abstracts and full texts (when available) in an automated manner.

The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation I333A was found are listed after the table.

The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.

Point mutation I333A in NR1I3_HUMAN

Point mutation:	I333A
Domain:	LBD HELIX 10-11
General numbering (NucleaRDB):	1060
Protein:	NR1I3_HUMAN (NR1I3,CA)	Swiss-Prot Cross-reference table Family page
Protein isoforms	2
Other point mutations / same protein	List of mutations in NR1I3_HUMAN
Family alignments	1I3 Constitutive Androstane alpha (CAR1) 1I Vitamin D3-like (VDR,PXR,CAR) 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR
Other point mutations / same position	Position 384 in 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR family
Reference:	The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver. Zelko I, Sueyoshi T, Kawamoto T, Moore R, Negishi M Mol Cell Biol 2001 Apr;21(8):2838-46.	Medline
Other point mutations / same article	List
Text source	HTML and PDF full texts
Validation status	True positive

Relevant sentences:

I333A

To search for residue(s) that may regulate the nuclear translocation in the liver , various amino acid residues between positions 319 and 338 were mutated: S321A , I322A , Y326A , Y328A , I330A , I333A , and L336A
Y328A , I330A , I333A , and L336A

F.Horn (nucleardbcmbi.kun.nl), 21-Apr-2005