2005, NucleaRDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation A393P was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | A393P | |
| Domain: | Loop 5-6 | |
| General numbering (NucleaRDB): | - | |
| Protein: | O77255_CHOFU (non) | Swiss-Prot Cross-reference table Family page |
| Other point mutations / same protein | List of mutations in O77255_CHOFU | |
| Family alignments |
1H1 Ecdysone 1H Ecdysone-like (ECR,LXR,FXR) 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR | |
| Other point mutations / same position |
Position 418 in 1H Ecdysone-like (ECR,LXR,FXR) family Position 277 in 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR family | |
| Reference: | A single point mutation in ecdysone receptor leads to increased ligand specificity: implications for gene switch applications. Kumar MB, Fujimoto T, Potter DW, Deng Q, Palli SR Proc Natl Acad Sci U S A 2002 Nov 12;99(23):14710-5. | Medline |
| Other point mutations / same article | List | |
| Text source | PDF full text | |
| Validation status | True positive |
Relevant sentences:
A393P
cmbi.kun.nl), 21-Apr-2005