NucleaRDB: Extraction of mutation data from the literature

This page lists the (extracted) point mutations found at one given position in one family multiple sequence alignment.

Point mutation(s) at position 381 ( 1057 - LBD HELIX 10-11 ) in 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR family

See the multiple sequence alignment with the mutation data

Swiss-Prot ID   (AC)            Protein subfamily                    Point mutation
NR1H3_HUMAN   (Q13133)   1H3 Oxysterol LXR alpha                          H421A        Wang M et al.,2003
NR1I3_HUMAN   (Q14994)   1I3 Constitutive Androstane alpha (CAR1)         I330A        Zelko I et al.,2001
NR1I3_MOUSE   (O35627)   1I3 Constitutive Androstane alpha (CAR1)         Y336A        Andersin T et al.,2003
NR1I3_MOUSE   (O35627)   1I3 Constitutive Androstane alpha (CAR1)         Y336C        Andersin T et al.,2003
NR1I3_MOUSE   (O35627)   1I3 Constitutive Androstane alpha (CAR1)         Y336F        Andersin T et al.,2003
PXR_HUMAN     (O75469)   1I2 Pregnane X (PXR)                             H407A        Ostberg T et al.,2002
PXR_HUMAN     (O75469)   1I2 Pregnane X (PXR)                             H407Q        Watkins RE et al.,2003
PXR_MOUSE     (O54915)   1I2 Pregnane X (PXR)                             Q404H        Ostberg T et al.,2002
THB1_MOUSE    (P37242)   1A2 Thyroid hormone beta                         H435L        Yen P et al.,2003
VDR_HUMAN     (P11473)   1I1 Vitamin D3 (VDR)                             H397A        Yamamoto K et al.,2000
VDR_HUMAN     (P11473)   1I1 Vitamin D3 (VDR)                             H397A        Verlinden L et al.,2003

F.Horn (nucleardbcmbi.kun.nl), 21-Apr-2005