A resting neutrophil responds to chemoattractant supplied by micropipet (left). (Quicktime movie)

After 35 years, Henry Bourne closed his laboratory in October, 2007. As an emeritus professor at UCSF, he participates in the scientific enterprise by attending seminars and meetings of several laboratories and helping others to prepare work for publication. In addition, he hopes to write a book about the lives and motivations of experimental biologists.

This website summarizes some of the work from Bourne’s laboratory, under the headings below.

• Neutrophil polarity: GPCRs, G proteins and the actin cytoskeleton
• Neutrophil chemotaxis (direction-finding)
• Molecular mechanism of GPCR activation
• Human G protein mutations that cause heritable disease

Henry Bourne’s Research

We can be reached at:

UCSF
600 16th Street
Room N212F, Box 2140
San Francisco, CA 94143
Courier zip code: 94107

Telephone #s: 415-476-8161 (Henry Bourne)

bourne@cmp.ucsf.edu

• Lab alumni
• G protein-alpha chimeras, see Bruce Conklin, a former postdoc in the lab
• Recent published papers (1996-present).
• Henry's CV
• Complete bibliography
• Department of Cellular and Molecular Pharmacology
• University of California at San Francisco

Last updated December 4, 2007.